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Article

Elevated DNA polymerase iota (Poli) is involved in the acquisition of aggressive phenotypes of human esophageal squamous cell cancer.

International journal of clinical and experimental pathology - 1 Jan 2015

Sun Haoyao, Zou Shitao, Zhang Shuyu, Liu Biao, Meng Xingjun, Li Xiaoqing, Yu Jian, Wu Jinchang, Zhou Jundong

Abstract excerpt

DNA polymerase iota (Polι) can repair several types of DNA damage but has extremely low fidelity. Previous studies have shown an aberrantly elevated Polι expression in human esophageal squamous cell cancer tissues. However, there were few reports describing the role of Polι in esophageal cancer progression. Based on Real-time PCR assay, we found Polι expression was up-regulated in esophageal cancer tissues...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26097541
PMCID: PMC4466928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Elevated DNA polymerase iota (Poli) is involved in the acquisition of aggressive phenotypes of human esophageal squamous cell cancer.PMID 26097541Read ↗

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