Article
The HLA class I A locus affects susceptibility to type 1 diabetes.
Human immunology - 1 Aug 2002
Noble Janelle A, Valdes Ana M, Bugawan Teodorica L, Apple Raymond J, Thomson Glenys, Erlich Henry A
Abstract excerpt
Human leukocyte antigen A (HLA-A) genotypes were determined for samples from 283 multiplex, Caucasian, type 1 diabetes families from the Human Biological Data Interchange (HBDI) using an immobilized probe assay. Distribution of HLA-A alleles transmitted to patients was significantly different from that in affected family-based controls (AFBAC) (p = 0.004). Transmission disequilibrium test (TDT) analysis revealed...
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