Article
Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 2002
Moodie S J, Norman P J, King A L, Fraser J S, Curtis D, Ellis H J, Vaughan R W, Ciclitira P J
Abstract excerpt
Coeliac disease is strongly heritable, with more than half of the genetic susceptibility estimated to come from genes outside the HLA region. Several candidate regions have been suggested from genome-wide linkage studies including chromosome 19q13.4 where linkage has been replicated between populations. The natural killer (NK) cell immunoglobulin-like receptors (KIRs) and leukocyte immunoglobulin-like receptor...
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