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Article

A combined genetics and genomics approach to unravelling molecular pathways in coeliac disease.

Novartis Foundation symposium - 1 Jan 2005

Wapenaar Martin C, Wijmenga Cisca

Abstract excerpt

Coeliac disease (CD) is a complex, inflammatory disorder of the small intestine induced by gluten. It is common and has a prevalence of approximately 1:200 in Western populations. A major known susceptibility locus for CD is the HLA -DQ locus. However, the genetic contribution of this region is limited to approximately 40%, so non-HLA genes must also be involved in the disease aetiology. Genetic studies have so...

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PMID: 15999804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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