Article
Oral lichen planus has a high rate of TP53 mutations. A study of oral mucosa in icelanD.
European journal of oral sciences - 1 Jun 2002
Ogmundsdóttir Helga M, Hilmarsdóttir Hólmfríöur, Astvaldsdóttir Alfheiöur, Jóhannsson Jóhann Heiöar, Holbrook W Peter
Abstract excerpt
Oral squamous cell carcinoma (OSCC) is a world-wide health problem. In addition to external exposure (smoking and alcohol), certain oral lesions may increase the risk of oral cancer (e.g. leukoplakia, erythroplakia, and oral lichen planus). TP53 has been implicated in OSCC, but there are limited studies of mutations in premalignant oral lesions. In this study, 55 samples from OSCC, 47 from hyperkeratotic (HK)...
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