Evaluation of p53 Gene Mutations in Oral Lichen Planus Lesions in a Population From Iran.

Abstract excerpt

OBJECTIVES: Oral lichen planus (OLP) is a chronic inflammatory disorder of the oral mucosa, genetic and molecular alterations, including mutations in the p53 tumor suppressor gene, have been implicated in OLP pathogenesis. However, its molecular mechanisms are not clearly understood. This study investigates p53 gene mutations in OLP lesions. MATERIAL AND METHODS: This study analyzed 43 paraffin-embedded tissue...

Topics

• Humans
• Lichen Planus, Oral
• Female
• Male
• Middle Aged
• Iran
• Mutation