Article
DNA mismatch repair, microsatellite instability and cancer.
Indian journal of experimental biology - 1 Sept 2002
Vaish Minal, Mittal B
Abstract excerpt
Mismatch (MMR) repair system plays a significant role in restoration of stability in the genome. Mutations in mismatch repair genes hamper their activity thus bring about a defect in mismatch repair (MMR) mechanism thereby conferring instability in the microsatellite sequences of both the coding and non-coding regions of the genome. Mutated mismatch repair genes result in the expansion or contraction of...
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