Article
Conversion of cerebral cortex into basal ganglia in Emx2(-/-) Pax6(Sey/Sey) double-mutant mice.
Nature neuroscience - 1 Aug 2002
Muzio Luca, Di Benedetto Barbara, DiBenedetto Barbara, Stoykova Anastassia, Boncinelli Edoardo, Gruss Peter, Mallamaci Antonello
Abstract excerpt
The molecular mechanisms that activate morphogenesis of cerebral cortex are currently the subject of intensive experimental analysis. Transcription factor genes of the homeobox, basic helix-loop-helix (bHLH) and zinc-finger families have recently been shown to have essential roles in this process. However, the actual selector genes activating corticogenesis have not yet been identified. Here we show that...
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