Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emx2 and Pax6 control regionalization of the pre-neuronogenic cortical primordium.

Cerebral cortex (New York, N.Y. : 1991) - 1 Feb 2002

Muzio Luca, Di Benedetto Barbara, DiBenedetto Barbara, Stoykova Anastassia, Boncinelli Edoardo, Gruss Peter, Mallamaci Antonello

Abstract excerpt

It has recently been demonstrated that the transcription factor genes Emx2 and Pax6, expressed in the developing cerebral cortex along two complementary tangential gradients, are essential for the shaping of the cortical areal profile at late developmental ages, when cortical neuronogenesis is al...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebral Cortex
Share to Eye Proteins
Share to Paired Box Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PAX6 Transcription Factor

Share to Receptor, Fibroblast Growth Factor, Type 3

Share to Receptors, Fibroblast Growth Factor

Share to Wnt Proteins

Share to Zebrafish Proteins

Source

Identifiers

PMID: 11739261
DOI: 10.1093/cercor/12.2.129

Genes

EMX2
PAX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11739261-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emx2 and Pax6 control regionalization of the pre-neuronogenic cortical primordium.PMID 11739261Read ↗

The lack of Emx2 causes impairment of Reelin signaling and defects of neuronal migration in the developing cerebral cortex.Semantic proximity Read ↗

Emx1 and Emx2 cooperate to regulate cortical size, lamination, neuronal differentiation, development of cortical efferents, and thalamocortical pathfinding.Semantic proximity Read ↗

Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex.Semantic proximity Read ↗

Embryonic signaling centers expressing BMP, WNT and FGF proteins interact to pattern the cerebral cortex.Semantic proximity Read ↗

Emx2 patterns the neocortex by regulating FGF positional signaling.Semantic proximity Read ↗

LIM-homeodomain gene Lhx2 regulates the formation of the cortical hem.Semantic proximity Read ↗

Conversion of cerebral cortex into basal ganglia in Emx2(-/-) Pax6(Sey/Sey) double-mutant mice.Semantic proximity Read ↗

RFX4 maintains excitatory–inhibitory balance through WNT-dependent cortical patterning: implications for neurodevelopmental disordersSemantic proximity Read ↗

The transcription factor, Pax6, is required for cell proliferation and differentiation in the developing cerebral cortex.Semantic proximity Read ↗

Evidence that Dmrta2 acts as a transcriptional repressor of <i>Pax6</i> in murine cortical progenitors and identification of a mutation crucial for DNA recognition associated with microcephaly in humanSemantic proximity Read ↗

Genetic regulation of arealization of the neocortex.Semantic proximity Read ↗

Pax6 regulates regional development and neuronal migration in the cerebral cortex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.