Article
Emx2 and Pax6 control regionalization of the pre-neuronogenic cortical primordium.
Cerebral cortex (New York, N.Y. : 1991) - 1 Feb 2002
Muzio Luca, Di Benedetto Barbara, DiBenedetto Barbara, Stoykova Anastassia, Boncinelli Edoardo, Gruss Peter, Mallamaci Antonello
Abstract excerpt
It has recently been demonstrated that the transcription factor genes Emx2 and Pax6, expressed in the developing cerebral cortex along two complementary tangential gradients, are essential for the shaping of the cortical areal profile at late developmental ages, when cortical neuronogenesis is almost completed. In this study we addressed the question of whether cortical regionalization is already affected in Emx2...
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