Article
Xenopus Meis3 protein lies at a nexus downstream to Zic1 and Pax3 proteins, regulating multiple cell-fates during early nervous system development.
Developmental biology - 1 Feb 2010
Gutkovich Yoni E, Ofir Rachel, Elkouby Yaniv M, Dibner Charna, Gefen Aharon, Elias Sarah, Frank Dale
Abstract excerpt
In Xenopus embryos, XMeis3 protein activity is required for normal hindbrain formation. Our results show that XMeis3 protein knock down also causes a loss of primary neuron and neural crest cell lineages, without altering expression of Zic, Sox or Pax3 genes. Knock down or inhibition of the Pax3,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.