Article
Embryonic cortical neural stem cells migrate ventrally and persist as postnatal striatal stem cells.
The Journal of cell biology - 9 Oct 2006
Willaime-Morawek Sandrine, Seaberg Raewyn M, Batista Claudia, Labbé Etienne, Attisano Liliana, Gorski Jessica A, Jones Kevin R, Kam Angela, Morshead Cindi M, van der Kooy Derek
Abstract excerpt
Embryonic cortical neural stem cells apparently have a transient existence, as they do not persist in the adult cortex. We sought to determine the fate of embryonic cortical stem cells by following Emx1(IREScre); LacZ/EGFP double-transgenic murine cells from midgestation into adulthood. Lineage tracing in combination with direct cell labeling and time-lapse video microscopy demonstrated that Emx1-lineage...
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