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The diabetes-prone NZO/HlLt strain. I. Immunophenotypic comparison to the related NZB/BlNJ and NZW/LacJ strains.

Laboratory investigation; a journal of technical methods and pathology - 1 Jul 2002

Haskell Bradford D, Flurkey Kevin, Duffy Theodore M, Sargent Evelyn E, Leiter Edward H

Abstract excerpt

New Zealand Obese (NZO)/HlLt male mice exhibit a polygenic obesity and approximately 50% develop type 2 diabetes. This strain is known to produce a variety of autoantibodies, including autoantibodies to the insulin receptor. Because of their relatedness to the autoimmune-predisposed New Zealand Black (NZB) and New Zealand White (NZW) inbred strains, we compared NZO to its two related strains for shared...

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PMID: 12118085
DOI: 10.1097/01.lab.0000018915.53257.00

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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