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Article

Characterisation of the mouse diabetes susceptibilty locus Nidd/SJL: islet cell destruction, interaction with the obesity QTL Nob1, and effect of dietary fat.

Diabetologia - 1 Jun 2002

Plum L, Giesen K, Kluge R, Junger E, Linnartz K, Schürmann A, Becker W, Joost H-G

Abstract excerpt

AIMS/HYPOTHESIS: The diabetes susceptibility locus Nidd/SJL was identified in an outcross of New Zealand obese (NZO) and lean Swiss/Jackson Laboratory mouse strain (SJL) mice. Here we characterise its effects in a NZO x F1(SJLxNZO) backcross population raised on high-fat or standard diet, and describe its interaction with the obesity quantitative trait locus (QTL) Nob1. METHODS: NZO x F1(SJLxNZO) backcross mice...

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Source

Identifiers

PMID: 12107726
DOI: 10.1007/s00125-002-0796-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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