Cystathionine β‐synthase is coordinately regulated with proliferation through a redox‐sensitive mechanism in cultured human cells and <i>Saccharomyces cerevisiae</i>

Abstract excerpt

Cystathionine beta-synthase (CBS) catalyzes the condensation of serine with homocysteine to form cystathionine and occupies a crucial regulatory position between the methionine cycle and the biosynthesis of cysteine by transsulfuration. Analysis of CBS activity under a variety of growth conditions indicated that CBS is coordinately regulated with proliferation in both yeast and human cells. In batch cultures of...

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