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Article

The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis.

The EMBO journal - 15 Feb 1999

Guo W, Roth D, Walch-Solimena C, Novick P

Abstract excerpt

Polarized secretion requires proper targeting of secretory vesicles to specific sites on the plasma membrane. Here we report that the exocyst complex plays a key role in vesicle targeting. Sec15p, an exocyst component, can associate with secretory vesicles and interact specifically with the rab GTPase, Sec4p, in its GTP-bound form. A chain of protein-protein interactions leads from Sec4p and Sec15p on the...

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Identifiers

PMID: 10022848
DOI: 10.1093/emboj/18.4.1071
PMCID: PMC1171198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis.PMID 10022848Read ↗

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