Polymorphisms in the apolipoprotein E (APOE) gene in gerontopsychiatric patients.

doi:10.1007/s004060170063

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Article

Polymorphisms in the apolipoprotein E (APOE) gene in gerontopsychiatric patients.

European archives of psychiatry and clinical neuroscience - 1 Jan 2001

Zill P, Engel R, Hampel H, Behrens S, Bürger K, Padberg F, Stübner S, Möller H J, Ackenheil M, Bondy B

Abstract excerpt

Two recently described polymorphisms in the promoter region of the apolipoprotein E (APOE), the -491A/T and Th1/E47csT/G polymorphism, have been suggested to be associated with an increased risk for Alzheimer's disease (AD) independent from the APOE epsilon 4 carrier status. We studied the association between the APOE epsilon 4 polymorphism and the -491A/T and Th1E47csT/G polymorphisms in a sample of 118 healthy,...

Topics

Aged
Alleles
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Diagnosis, Differential
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Male
Middle Aged
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 11315514
DOI: 10.1007/s004060170063

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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