Article
Role of G protein beta3 subunit C825T and HLA class II polymorphisms in the immune response after HBV vaccination.
Virology - 5 Jun 2002
Lindemann Monika, Barsegian Vahé, Siffert Winfried, Ferencik Stanislav, Roggendorf Michael, Grosse-Wilde Hans
Abstract excerpt
The G protein beta3 (GNB3) subunit and HLA are candidate genes predictive of immune response capacity. We therefore studied the influence of both gene systems on cellular and humoral immunity against hepatitis B virus (HBV) in 79 HBV booster-vaccinated healthy volunteers and an independent group of 77 probands after HBV basic immunization. Following booster vaccination, lymphocyte in vitro proliferation after...
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