Article
SNP rs7770370 in HLA-DPB1 loci as a major genetic determinant of response to booster hepatitis B vaccination: results of a genome-wide association study.
Journal of gastroenterology and hepatology - 1 May 2015
Wu Tzu-Wei, Chen Chuen-Fei, Lai Sheng-Kai, Lin Hans Hsienhong, Chu Chen-Chung, Wang Li-Yu
Abstract excerpt
BACKGROUND AND AIM: Hepatitis B (HB) vaccination is highly effective in reducing the risk of hepatitis B virus infection. However, breakthrough and chronic hepatitis B virus infections in vaccinated subjects raised concern about its long-term efficacy. The specific aim of the study was to explore the host genetic determinants of long-term immunological memory against HB vaccination. METHODS: We conducted a...
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