Article
Effects of interleukin-4 and interleukin-12B gene polymorphisms on hepatitis B virus vaccination.
Annals of hepatology - 1 Jan 2000
Roh Eun Youn, Song Eun Young, Yoon Jong Hyun, Oh Sohee, Chang Ju Young, Park Hyunwoong, Seo Soo Hyun, Shin Sue
Abstract excerpt
Approximately 10% of individuals do not respond to hepatitis B virus (HBV) vaccination, i.e. non-responders (NRs). We aimed to investigate the association of interleukin (IL)-4 and IL-12B gene polymorphisms with responsiveness to the HBV vaccine in Korean infants. Among 300 healthy infants (9-12 month), SNPs for the IL-4 gene (rs2243250, rs2070874, and rs2227284) and for the IL-12B gene (rs3213094 and rs17860508)...
