Article
Distinct HLA class II alleles determine antibody response to vaccination with hepatitis B surface antigen.
Kidney international - 1 Jun 1998
Caillat-Zucman S, Gimenez J J, Wambergue F, Albouze G, Lebkiri B, Naret C, Moynot A, Jungers P, Bach J F
Abstract excerpt
Major histocompatibility complex (MHC) determinants control antibody production in response to protein antigens. Vaccination with hepatitis B surface antigen (HBsAg) frequently fails in hemodialyzed patients, but the genetic factors that modulate humoral responsiveness are poorly characterized. We studied the distribution of HLA class II alleles in 415 hemodialyzed Caucasian patients who received a full course of...
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