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Article

Genotype of CYP3AP1 associated with CYP3A activity in Chinese Han population.

Acta pharmacologica Sinica - 1 Jun 2002

Zhu Bing, Chen Guo-Lin, Chen Xiao-Ping, He Nan, Liu Zhao-Qian, Jiang Chang-Hong, Wang Dan, Zhou Hong-Hao

Abstract excerpt

AIM: To investigate the distribution of genotype of CYP3AP1 in Chinese Han population and the correlation with CYP3A activity. METHODS: Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was employed in CYP3AP1 genotype analysis; using midazolam as probe drug, CYP3A activity of 191 Chinese healthy subjects was measured by plasma 1'-hydroxymidazolam/midazolam (1'-OH-MDZ/MDZ) ratio at 1 h...

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PMID: 12060534

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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