Article
Effect of quercetin on CYP3A activity in Chinese healthy participants.
Journal of clinical pharmacology - 1 Jun 2012
Duan Kai-Ming, Wang Sai-Ying, Ouyang Wen, Mao Yan-Mei, Yang Li-Jun
Abstract excerpt
The aims of this study were to investigate the effect of quercetin on CYP3A activity in vivo. An open, randomized, 2-period crossover experiment was performed in 18 healthy male volunteers. Genotyped data were available from a total of 165 participants. The allelic frequency was 52.5%. Every volunteer ingested orally 500 mg quercetin or placebo once a day for 13 consecutive days. On day 14, a single 7.5-mg...
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