Typing dinucleotide repeats under nondenaturing conditions with single-base resolution and high sizing precision.

doi:10.1385/MB:21:2:117

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Article

Typing dinucleotide repeats under nondenaturing conditions with single-base resolution and high sizing precision.

Molecular biotechnology - 1 Jun 2002

Rodríguez Santiago, Zapata Carlos

Abstract excerpt

Dinucleotide repeats are genetic markers that are useful for many purposes, including genetic epidemiology, population genetics, and genetic diagnostics. The accuracy of analyses based on dinucleotide repeat polymorphisms is highly dependent on the success achieved in minimizing genotyping errors. Genotyping errors in dinucleotide repeat typing may arise for various reasons, including polymerase chain reaction...

Topics

Alleles
Electrophoresis, Polyacrylamide Gel
Female
Genetic Techniques
Genotype
Humans
Male
Pedigree
Polymerase Chain Reaction
Polymorphism, Genetic
Reproducibility of Results
Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 12059111
DOI: 10.1385/MB:21:2:117

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