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Article

Multiplex genotyping and allele frequency estimation in pooled DNAs using non-gel capillary electrophoresis.

Analytical biochemistry - 15 Apr 2009

Yin Bin-Cheng, Wang Xian-Fei, Ye Bang-Ce

Abstract excerpt

We present a novel approach of single-nucleotide polymorphism (SNP) analysis in which allele-specific oligonucleotide hybridization is followed by non-gel capillary electrophoresis (ASOH-NGCE) in conjunction with laser-induced fluorescence (LIF). This allows rapid multiplex allelotyping and allele frequency estimation. This method, based on site separation of the hybridization duplexes, retains the simplicity and...

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Identifiers

PMID: 19344657
DOI: 10.1016/j.ab.2009.01.021

Genes

LIF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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