Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of single nucleotide polymorphisms by PCR conformation-difference gel electrophoresis.

Biotechnology letters - 1 Apr 2013

Zhu Weifeng, Deng Yan, Jie Kemin, Luo Daya, Liu Zhuoqi, Yu Lehan, Zeng Erming, Wan Fusheng

Abstract excerpt

The most common genetic variations in the human genome, single nucleotide polymorphisms (SNPs), are ideal biomarkers and are used extensively in disease research. Here we introduce a novel method of PCR-conformation-difference gel electrophoresis (PCR-CDGE) used for detecting SNPs. The principle of PCR-CDGE relies PCR products from different homozygous DNA samples showing dissimilar migration patterns upon PAGE...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Costs and Cost Analysis
Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heteroduplex Analysis

Share to Molecular Biology

Share to Nucleic Acid Conformation

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Share to Time Factors

Source

Identifiers

PMID: 23250445
DOI: 10.1007/s10529-012-1115-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of single nucleotide polymorphisms by PCR conformation-difference gel electrophoresis.PMID 23250445Read ↗

High-throughput conformation-sensitive gel electrophoresis for discovery of SNPs.Semantic proximity Read ↗

Conformation sensitive gel electrophoresis.Semantic proximity Read ↗

Gel-based nonradioactive single-strand conformational polymorphism and mutation detection: limitations and solutions.Semantic proximity Read ↗

Gel-based nonradioactive single-strand conformational polymorphism and mutation detection: limitations and solutions.Semantic proximity Read ↗

Electrophoretic detection of single-nucleotide polymorphisms.Semantic proximity Read ↗

Single nucleotide polymorphism screening with denaturing gradient gel electrophoresis.Semantic proximity Read ↗

High-throughput methods for detection of genetic variation.Semantic proximity Read ↗

A multiplexing single nucleotide polymorphism typing method based on restriction-enzyme-mediated single-base extension and capillary electrophoresis.Semantic proximity Read ↗

Mutation detection by denaturing gradient gel electrophoresis (DGGE)Semantic proximity Read ↗

PCR-Based Detection Methods for Single-Nucleotide Polymorphism or Mutation: Real-Time PCR and Its Substantial Contribution Toward Technological Refinement.Semantic proximity Read ↗

Detection of multiple SNPs in numerous samples with polyacrylamide gel-based microarray.Semantic proximity Read ↗

Denaturing high-performance liquid chromatography for mutation detection and genotyping.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.