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Article

Alpha2-macroglobulin deletion polymorphism and plasma levels in late onset Alzheimer's disease.

Clinical chemistry and laboratory medicine - 1 Apr 2002

Scacchi Renato, Ruggeri Maria, Gambina Giuseppe, Martini Maria C, Corbo Rosa M

Abstract excerpt

The acute-phase "panproteinase" inhibitor alpha2-macroglobulin (alpha2M), a protein involved in inflammatory reactions, has been identified in amyloid plaques in Alzheimer's disease (AD). In addition, alpha2M is involved in AD susceptibility at the genetic level, and a deletion polymorphism at the a2M gene has been found to be associated with sporadic AD. We analyzed the deletion polymorphism and alpha2M plasma...

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Source

Identifiers

PMID: 12059070
DOI: 10.1515/CCLM.2002.052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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