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Article

Polymorphism in the STAT6 gene encodes risk for nut allergy.

Genes and immunity - 1 Jun 2002

Amoli M M, Hand S, Hajeer A H, Jones K P, Rolf S, Sting C, Davies B H, Ollier W E R

Abstract excerpt

Nut allergy is an important and potentially life threatening food allergy with a prevalence of one in 150 children in the UK population. STAT6 (signal transducer and activator of transcription) is an important molecule in the induction and regulation of an allergic response, which maps to chromosome 12q in a region previously linked with total serum IgE concentration and atopy in different populations. We have...

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Source

Identifiers

PMID: 12058257
DOI: 10.1038/sj.gene.6363872

Genes

STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Polymorphism in the STAT6 gene encodes risk for nut allergy.PMID 12058257Read ↗

Linkage and association studies of STAT6 gene polymorphisms and allergic diseases.Semantic proximity Read ↗

Novel dinucleotide repeat polymorphism in the first exon of the STAT-6 gene is associated with allergic diseases.Semantic proximity Read ↗

Association analysis of signal transducer and activator of transcription 4 (STAT4) polymorphisms with asthma.Semantic proximity Read ↗

Association of the STAT-6 rs324011 (C2892T) variant but not rs324015 (G2964A), with atopic asthma in a Saudi Arabian population.Semantic proximity Read ↗

Association of a STAT 6 haplotype with elevated serum IgE levels in a population based cohort of white adults.Semantic proximity Read ↗

Human leucocyte antigen polymorphisms in nut-allergic patients in South Wales.Semantic proximity Read ↗

Association of STAT6 gene variants with food allergy diagnosed by double-blind placebo-controlled food challenges.Semantic proximity Read ↗

Association of the STAT6 rs3024974 (C/T) Polymorphism with IgE-Mediated Food Sensitization among West Bengal Population in India.Semantic proximity Read ↗

STAT6 as an asthma candidate gene: polymorphism-screening, association and haplotype analysis in a Caucasian sib-pair study.Semantic proximity Read ↗

STAT1 gene variations, IgE regulation and atopy.Semantic proximity Read ↗

Variation in dinucleotide (GT) repeat sequence in the first exon of the <i>STAT6</i> gene is associated with atopic asthma and differentially regulates the promoter activity in vitroSemantic proximity Read ↗

Association of STAT6 and ADAM33 single nucleotide polymorphisms with asthma bronchiale and IgE level and its possible epigenetic background.Semantic proximity Read ↗

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