Article
Allele-specific analysis of transcription factors binding to promoter regions.
Methods (San Diego, Calif.) - 1 Jan 2002
Heckman Caroline A, Boxer Linda M
Abstract excerpt
In vivo footprinting techniques are useful for the identification of regulatory elements mediating transcriptional control of a gene. However, regulation of a gene can differ between the two alleles, and further steps must be taken to distinguish between the regulatory elements occupied on one allele and those used on the second allele. Many hematologic malignancies result from chromosomal translocations, which,...
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