A method to analyze allele-specific methylation.

Article

A method to analyze allele-specific methylation.

BioTechniques - 1 Dec 1990

Bedford M T, van Helden P D

Abstract excerpt

We have developed a method to analyze the methylation patterns of individual alleles of a gene. The target gene must have alleles identifiable by restriction fragment length polymorphism analysis. The method involves separation of the alleles after digestion by restriction enzyme digestion and el...

Topics

Alleles
DNA
Deoxyribonuclease BamHI
Female
Genes, ras
Humans
Male
Methylation
Polymorphism, Restriction Fragment Length
Repetitive Sequences, Nucleic Acid

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