In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome.

doi:10.1126/science.1902592

Back to search

Article

In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome.

Science (New York, N.Y.) - 3 May 1991

Kara C J, Glimcher L H

Abstract excerpt

Major histocompatibility complex (MHC) class II genes are coordinately regulated and show tissue-specific expression. With the use of in vivo footprinting, common promoter sites in these genes were found to be occupied only in cells that expressed the genes, in spite of the presence of the promot...

Topics

Animals
B-Lymphocytes
Base Sequence
Cell Line
DNA
Gene Expression
Genes, MHC Class II
Humans
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Promoter Regions, Genetic
Regulatory Sequences, Nucleic Acid
Syndrome

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.