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Article

In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome.

Science (New York, N.Y.) - 3 May 1991

Kara C J, Glimcher L H

Abstract excerpt

Major histocompatibility complex (MHC) class II genes are coordinately regulated and show tissue-specific expression. With the use of in vivo footprinting, common promoter sites in these genes were found to be occupied only in cells that expressed the genes, in spite of the presence of the promoter binding proteins. In vivo analysis of mutant cell lines that exhibited coordinate loss of class II MHC expression,...

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Identifiers

PMID: 1902592
DOI: 10.1126/science.1902592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Coordinate defects in human histocompatibility leukocyte antigen class II expression and antigen presentation in bare lymphocyte syndrome.Semantic proximity Read ↗

The DMB promoter: delineation, in vivo footprint, trans-activation, and trans-dominant suppression.Semantic proximity Read ↗

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