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Article

Human genome search in celiac disease: mutated gliadin T-cell-like epitope in two human proteins promotes T-cell activation.

Journal of molecular biology - 7 Jun 2002

Kumar Rajesh, Eastwood Amy L, Brown Milton L, Laurie Gordon W

Abstract excerpt

Discovery of a number of novel and known human genes whose protein products bear striking similarity to two or more wheat gliadin domains raised the possibility that human intestinal non-HLA peptides homologous to celiac T-cell epitopes could play a role in non-HLA gene specification in celiac disease. Database searching of the entire human genome identified only 11 gut-expressed proteins with high T-cell epitope...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12054857
DOI: 10.1016/S0022-2836(02)00366-2

Genes

FOXJ2
PAX9
PHLDA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Human genome search in celiac disease: mutated gliadin T-cell-like epitope in two human proteins promotes T-cell activation.PMID 12054857Read ↗

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