Article
New Insights on Genes, Gluten, and Immunopathogenesis of Celiac Disease.
Gastroenterology - 1 Jun 2024
Abadie Valérie, Han Arnold S, Jabri Bana, Sollid Ludvig M
Abstract excerpt
Celiac disease (CeD) is a gluten-induced enteropathy that develops in genetically susceptible individuals upon consumption of cereal gluten proteins. It is a unique and complex immune disorder to study as the driving antigen is known and the tissue targeted by the immune reaction can be interrogated. This review integrates findings gained from genetic, biochemical, and immunologic studies, which together have...
Topics
- Celiac Disease
- Humans
- Glutens
- Animals
- Genetic Predisposition to Disease
- B-Lymphocytes
- CD4-Positive T-Lymphocytes
