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Article

The myeloperoxidase gene in Alzheimer's disease: a case-control study and meta-analysis.

Neuroscience letters - 21 Jun 2002

Combarros Onofre, Infante Jon, Llorca Javier, Peña Nicolás, Fernández-Viadero Carlos, Berciano José

Abstract excerpt

Myeloperoxidase (MPO) presence has been demonstrated in microglia associated with senile plaques, and contributes to Alzheimer's disease (AD) pathology through oxidation-induced damage. Recently, a functional biallelic (G/A) polymorphism in the promotor region (-463) of the MPO gene has been associated with susceptibility to AD, but the reports of this association have been inconsistent. A case-control study...

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Source

Identifiers

PMID: 12052532
DOI: 10.1016/s0304-3940(02)00303-8

Genes

MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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