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Article

Myeloperoxidase polymorphisms in brain infarction. Association with infarct size and functional outcome.

Atherosclerosis - 1 Apr 2003

Hoy Aline, Leininger-Muller Brigitte, Poirier Odette, Siest Gérard, Gautier Marion, Elbaz Alexis, Amarenco Pierre, Visvikis Sophie

Abstract excerpt

Myeloperoxidase (MPO) has been shown to contribute to several diseases and more particularly to atherosclerosis through excessive ROS production via the MPO/H(2)O(2)/Cl(-) oxidation system. The aim of this study was to determine whether there is an association between MPO polymorphisms and brain infarction (BI), one of the main consequences of atherosclerosis. We investigated MPO G-463A and G-129A polymorphisms...

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Identifiers

PMID: 12818404
DOI: 10.1016/s0021-9150(02)00041-2

Genes

MPO

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