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Article

Association between Alzheimer's disease and a functional polymorphism in the Myeloperoxidase gene.

Experimental neurology - 1 Feb 2001

Crawford F C, Freeman M J, Schinka J A, Morris M D, Abdullah L I, Richards D, Sevush S, Duara R, Mullan M J

Abstract excerpt

A polymorphism in the Myeloperoxidase gene (MPO) has previously been demonstrated to be associated with gender-specific risk in an Alzheimer's Disease (AD) autopsy sample. We have investigated this polymorphism in our own samples of 226 Caucasian cases and 166 controls and 59 Hispanic cases and 75 controls. In Caucasians we find a significant association between MPO genotype and AD (P = 0.03), although we do not...

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Source

Identifiers

PMID: 11161635
DOI: 10.1006/exnr.2000.7560

Genes

MPO
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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