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Article

Myeloperoxidase polymorphism, menopausal status, and breast cancer risk: an update meta-analysis.

PloS one - 1 Jan 2013

Qin Xue, Deng Yan, Zeng Zhi-Yu, Peng Qi-Liu, Huang Xiu-Li, Mo Cui-Ju, Li Shan, Zhao Jin-Min

Abstract excerpt

Myeloperoxidase (MPO) is a metabolic/oxidative lysosomal enzyme secreted by reactive neutrophils at the sites of inflamed organs and tissues during phagocytosis. MPO has been either directly or indirectly linked to neoplasia, which is a well-established risk factor for many types of cancer. A large number of studies have reported the role of MPO G-463A polymorphism regarding breast-cancer risk. However, the...

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Identifiers

PMID: 23991124
DOI: 10.1371/journal.pone.0072583
PMCID: PMC3749128

Genes

MPO

Variants

Provenance

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