Article
Myeloperoxidase G-463A polymorphism and Alzheimer's disease in the ApoEurope study.
Neuroscience letters - 2 Oct 2003
Leininger-Muller Brigitte, Hoy Aline, Herbeth Bernard, Pfister Michèle, Serot Jean Marie, Stavljenic-Rukavina Marina, Massana Luis, Passmore P, Siest Gérard, Visvikis Sophie
Abstract excerpt
Alzheimer's disease (AD) is the most common cause of dementia in the elderly. Epidemiological and molecular genetic studies have shown the existence of several genes associated with increased risk of AD, the major genetic susceptibility locus coding for apolipoprotein E (apoE). A polymorphism in the myeloperoxidase gene (MPO) has previously been associated with AD susceptibility. However, results in the...
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