Article
Regulation of Saccharomyces cerevisiae FET4 by oxygen and iron.
Journal of molecular biology - 26 Apr 2002
Jensen Laran T, Culotta Valeria Cizewski
Abstract excerpt
Saccharomyces cerevisiae expresses two distinct iron transport systems under aerobic and anaerobic conditions. The high affinity transporters, Ftr1p and Fet3p, are primarily expressed in oxygenated cultures, whereas anaerobic conditions induce the low affinity iron transporter, Fet4p. The oxygen regulation of FET4 was found to involve the Rox1p transcriptional repressor. The physiological significance of this...
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