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Article

Dynamic localization of an Okazaki fragment processing protein suggests a novel role in telomere replication.

Molecular and cellular biology - 1 Jun 2002

Choe Wonchae, Budd Martin, Imamura Osamu, Hoopes Laura, Campbell Judith L

Abstract excerpt

We have found that the Dna2 helicase-nuclease, thought to be involved in maturation of Okazaki fragments, is a component of telomeric chromatin. We demonstrate a dynamic localization of Dna2p to telomeres that suggests a dual role for Dna2p, one in telomere replication and another, unknown function, perhaps in telomere capping. Both chromatin immunoprecipitation (ChIP) and immunofluorescence show that Dna2p...

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Source

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Identifiers

PMID: 12024033
DOI: 10.1128/MCB.22.12.4202-4217.2002
PMCID: PMC133873

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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