Article
Molecular phenotype distinguishes two subsets of gastric low-grade mucosa-associated lymphoid tissue lymphomas.
Laboratory investigation; a journal of technical methods and pathology - 1 May 2002
Nardini Elena, Rizzi Simona, Ménard Sylvie, Balsari Andrea
Abstract excerpt
Isotype switch recombination together with somatic mutation of immunoglobulin variable genes is indicative of B-cell maturation stage. Because aberrant isotype switch events occur in a proportion of gastric mucosa-associated lymphoid tissue (MALT) lymphomas, we tested whether gastric MALT lymphomas with or without aberrant rearrangements in the switch regions differ in B-cell maturation stage. Southern blot...
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