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Article

Somatic hypermutation in low-grade mucosa-associated lymphoid tissue- type B-cell lymphoma

1 Nov 1995

Abstract excerpt

The origin of low-grade mucosa-associated lymphoid tissue (MALT)-type B-cell lymphoma is still unclear. Using a novel two-step procedure, we have sequenced the Ig VH genes expressed by cells from four patients with gastric low-grade MALT-type lymphoma. The nucleotide sequences of the complementarity determining region 3 (CDR3) of the genomic DNA were first amplified using consensus oligonucleotide primers, then...

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Identifiers

PMID: 7579460
DOI: 10.1182/blood.v86.9.3528.bloodjournal8693528

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Somatic hypermutation in low-grade mucosa-associated lymphoid tissue- type B-cell lymphomaPMID 7579460Read ↗

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Characterization of genetic events involving IgH switch regions in gastric low-grade MALT lymphomas and B-CLLSemantic proximity Read ↗

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