Article
Gastric MALT lymphoma B cells express polyreactive, somatically mutated immunoglobulins.
Blood - 21 Jan 2010
Craig Vanessa J, Arnold Isabelle, Gerke Christiane, Huynh Minh Q, Wündisch Thomas, Neubauer Andreas, Renner Christoph, Falkow Stanley, Müller Anne
Abstract excerpt
Gastric B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) arises against a background of chronic inflammation caused by persistent Helicobacter pylori infection. The clinical and histopathologic features of the human tumor can be reproduced by Helicobacter infection of BALB/c mice. In this study, we have analyzed the antibody sequences and antigen specificity of a panel of murine and human MALT...
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