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Article

Ongoing mutation in MALT lymphoma immunoglobulin gene suggests that antigen stimulation plays a role in the clonal expansion.

Leukemia - 1 Jul 1996

Du M, Diss T C, Xu C, Peng H, Isaacson P G, Pan L

Abstract excerpt

Indirect antigenic stimulation by H. pylori-specific T cells is implicated in the development of low-grade gastric lymphoma of mucosa-associated lymphoid tissue (MALT), however, the role of direct antigen stimulation is unknown. To study the role of direct antigen stimulation in MALT lymphomagene...

Topics

Animals
Antigens
Base Sequence
Female
Gene Rearrangement, B-Lymphocyte, Heavy Chain
Genes, Immunoglobulin
Humans
Lymphoma, B-Cell, Marginal Zone
Lymphoma, Non-Hodgkin
Male
Molecular Sequence Data
Mutation

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Identifiers

PMID: 8684001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8684001-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Ongoing mutation in MALT lymphoma immunoglobulin gene suggests that antigen stimulation plays a role in the clonal expansion.PMID 8684001Read ↗

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Somatic hypermutation in low-grade mucosa-associated lymphoid tissue- type B-cell lymphomaSemantic proximity Read ↗

Intraclonal offspring expansion of gastric low-grade MALT-type lymphoma: evidence for the role of antigen-driven high-affinity mutation in lymphomagenesis.Semantic proximity Read ↗

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Molecular phenotype distinguishes two subsets of gastric low-grade mucosa-associated lymphoid tissue lymphomas.Semantic proximity Read ↗

Effect of Helicobacter pylori eradication on ongoing mutation of immunoglobulin genes in gastric MALT lymphoma.Semantic proximity Read ↗

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Characterization of genetic events involving IgH switch regions in gastric low-grade MALT lymphomas and B-CLLSemantic proximity Read ↗

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