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Article

Significant association between TNFAIP3 inactivation and biased immunoglobulin heavy chain variable region 4-34 usage in mucosa-associated lymphoid tissue lymphoma.

The Journal of pathology - 1 Sept 2017

Moody Sarah, Escudero-Ibarz Leire, Wang Ming, Clipson Alexandra, Ochoa Ruiz Eguzkine, Dunn-Walters Deborah, Xue Xuemin, Zeng Naiyan, Robson Alistair, Chuang Shih-Sung, Cogliatti Sergio, Liu Hongxiang, Goodlad John, Ashton-Key Margaret, Raderer Markus, Bi Yingwen, Du Ming-Qing

Abstract excerpt

Both antigenic drive and genetic change play critical roles in the development of mucosa-associated lymphoid tissue (MALT) lymphoma, but neither alone is sufficient for malignant transformation, and lymphoma development critically depends on their cooperation. However, which of these different events concur and how they cooperate in MALT lymphomagenesis is totally unknown. To explore this, we investigated somatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, Immunoglobulin Heavy Chain

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Share to Lymphoma, B-Cell, Marginal Zone

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Source

Identifiers

PMID: 28682481
DOI: 10.1002/path.4933

Genes

TNFAIP3
CARD11
MYD88
TRAF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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