Article
Strain-specific patterns of autonomic nervous system activity and heart failure susceptibility in mice.
American journal of physiology. Heart and circulatory physiology - 1 Jun 2002
Shusterman Vladimir, Usiene Irmute, Harrigal Chivonne, Lee Joon Sup, Kubota Toru, Feldman Arthur M, London Barry
Abstract excerpt
Transgenic mice are widely used to study cardiac function, but strain-dependent differences in autonomic nervous system activity (ANSA) have not been explored. We compared 1) short-term pharmacological responses of cardiac rhythm in FVB vs. C57Black6/SV129 wild-type mice and 2) long-term physiological dynamics of cardiac rhythm and survival in tumor necrosis factor (TNF)-alpha transgenic mice with heart failure...
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