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Article

Genetic background affects function and intracellular calcium regulation of mouse hearts.

Cardiovascular research - 1 Sept 2010

Shah Adarsh P, Siedlecka Urszula, Gandhi Ajay, Navaratnarajah Manoraj, Al-Saud Sara Abou, Yacoub Magdi H, Terracciano Cesare M

Abstract excerpt

AIMS: The genetic background is currently under close scrutiny when determining cardiovascular disease progression and response to therapy. However, this factor is rarely considered in physiological studies, where it could influence the normal behaviour and adaptive responses of the heart. We aim to test the hypothesis that genetic strain variability is associated with differences in excitation-contraction...

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Source

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PMID: 20413651
DOI: 10.1093/cvr/cvq111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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