Article
Phenotypic screening for heart rate variability in the mouse.
American journal of physiology. Heart and circulatory physiology - 1 Aug 2000
Gehrmann J, Hammer P E, Maguire C T, Wakimoto H, Triedman J K, Berul C I
Abstract excerpt
We developed a technology for heart rate (HR) variability (HRV) analysis in the mouse for characterization of HR dynamics, modulated by vagal and sympathetic activity. The mouse is the principal animal model for studying biological processes. Mouse strains are now available harboring gene mutations providing fundamental insights into molecular mechanisms underlying cardiac electrical diseases. Future progress...
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