Article
High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred mouse strains.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology - 1 Aug 2014
Moreth Kristin, Fischer Ralf, Fuchs Helmut, Gailus-Durner Valérie, Wurst Wolfgang, Katus Hugo A, Bekeredjian Raffi, Hrabě de Angelis Martin
Abstract excerpt
Mice with genetic alterations are used in heart research as model systems of human diseases. In the last decade there was a marked increase in the recognition of genetic diversity within inbred mouse strains. Increasing numbers of inbred mouse strains and substrains and analytical variation of cardiac phenotyping methods require reproducible, high-throughput methods to standardize murine cardiovascular...
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