Article
Naturally occurring variation in cardiovascular traits among inbred mouse strains.
Genomics - 1 May 2002
Hoit Brian D, Kiatchoosakun Songsak, Restivo Joseph, Kirkpatrick Darryl, Olszens Keith, Shao Haifeng, Pao Yoh-Han, Nadeau Joseph H
Abstract excerpt
The objective of this study was to characterize genetic variation in complex cardiovascular traits in two commonly used inbred mouse strains. We performed echocardiography, graded treadmill exercise, tail cuff plethysmography, and telemetry (heart rate, activity, temperature) in age- ( approximately 9 weeks) and sex-matched A/J and C57BL/6J (B6) inbred mice. B6 mice had significantly larger end-diastolic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
