Article
Genetic influence on electrocardiogram time intervals and heart rate in aging mice.
American journal of physiology. Heart and circulatory physiology - 1 Jun 2009
Xing Shuqin, Tsaih Shirng-Wreng, Yuan Rong, Svenson Karen L, Jorgenson Linda M, So Milly, Paigen Beverly J, Korstanje Ron
Abstract excerpt
Understanding the genetic influence on ECG time intervals and heart rate (HR) is important for identifying the genes underlying susceptibility to cardiac arrhythmias. The objective of this study was to determine the genetic influence on ECG parameters and their age-related changes in mice. ECGs were recorded in lead I on 8 males and 8 females from each of 28 inbred strains at the ages of 6, 12, and 18 mo....
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